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The 1st NanoLSI Symposium – Towards Establishment of New Research Field: Nanoprobe Life Science-

The 1st NanoLSI Symposium was held at Miraikan – National Museum of Emerging Science and Innovation on February 21and 22, 2018, and approximately 120 researchers participated in.
This symposium was the first step to enhance the visibility of NanoLSI as a worldwide research core, and NanoLSI expressed the strong mind that it aimed for fundamental understanding of various life phenomena through combining Nanometrology, Life Science, Supramolecular Chemistry and Computational Science.
To mark the opening of this symposium, Prof. Takeshi Fukuma, Center Director of NanoLSI explained how NanoLSI came to be launched and what we were aiming for. Then, Koetsu Yamazaki, president of Kanazawa University, Keisuke Isogai, Director-General of Research Promotion Bureau at the Ministry of Education, Culture, Sports, Science and Technology and Akira Ukawa, the WPI Program Director gave the remarks.
In each session, principal investigators of NanoLSI presented their research and invited researchers gave the talks regarding their recent works.
Furthermore, participants discussed research achievements and research approaches actively in front of poster presentations, too.
Through two days, there were many ideas and suggestions for the transdisciplinary research in NanoLSI to create new research field “Nanoprobe Life Science”, and researchers of NanoLSI strongly renewed their determination to achieve it.

Session1　Visualizing structures and dynamics of biological systems

• High-resolution & 3D atomic force microscopy for visualizing nanobiointerfaces
  Prof. Takeshi Fukuma (NanoLS)
• High-speed atomic force microscopy: Visualizing protein molecules in action
  Prof. Toshio Ando (NanoLSI)
• Nanopipette biosensors for single-cell analysis
  Prof. Yuri E. Korchev (Imperial College London, NanoLSI)

Session2　Computing the structure and dynamics of biological molecules

• Dynamics of Biological Active Matter at Nanoscales: Theoretical approaches
  Prof. Alexander S.Mikhailov (Fritz Haber Institute of the Max Planck Society, NanoLSI)
• Designing molecules and deciphering their biological functions with the aid of computer simulations, dream or reality?
  Prof. Mikko Karttunen (Western University)

Session3　 Dynamic Nanomachines and Nanomedicine

• Growth Factor Signaling: Dynamics, Cancer, and Drug Discovery
  Prof. Kunio Matsumoto (NanoLSI)
• Structures and dynamics of macromolecular motors revealed by electron cryomicroscopy and optical nanophotometry
  Prof. Keiichi Namba (Osaka University）
• Spatiotemporal dynamics of the nuclear nanomachine – the nuclear pore complex
  Prof. Richard W. Wong (NanoLSI)

Session4　 New aspects of supramolecular chemistry

• Pillar[n]arenes:From simple molecular receptors to bulk supramolecular assemblies
  Prof. Tomoki Ogoshi (NanoLSI)
• Anion recognition: Capture, release, and selectivity in synthetic receptors
  Prof. Amar H. Flood (Indiana University)
• Supramolecular Chemistry with Macrocycles
  Prof. Mark J. MacLachlan (University of British Columbia, NanoLSI)