NanoLSI Transdisciplinary Research Promotion Seminar “Computational tools to characterize structure and dynamics of biomolecular systems from single molecule experiments”
The NanoLSI Transdisciplinary Research Promotion Seminar “Computational tools to characterize structure and dynamics of biomolecular systems from single molecule experiments”
On May 21, NanoLSI held the Open Seminar “Computational tools to characterize structure and dynamics of biomolecular systems from single molecule experiments” at Natural Science Library Hall, Kanazawa University.
In the seminar, Prof. Florence Tama from the Institute of Transformative Bio-Molecules (WPI-ITbM), Nagoya University and the RIKEN Center for Computational Science in Kobe described computational methods to process and interpret the data from single-particle observations of biomolecules. She has shown how hybrid computational methods combining molecular dynamics simulations on modern supercomputers and massive image processing algorithms are used at RIKEN to derive structural and dynamical information for proteins from the data of cryo electron microscopy (cryo-EM) and X-ray free electron laser (XFEL) experiments.
It has been further discussed whether similar methods can be developed to process the data and to reconstruct conformational dynamics of proteins in the experiments with High-speed Atomic Force Microscope (HS-AFM).
Dr. Florence Tama
